Serveur d'exploration sur la maladie de Parkinson

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Diet and Parkinson's disease: A potential role of dairy products in men

Identifieur interne : 001909 ( Main/Exploration ); précédent : 001908; suivant : 001910

Diet and Parkinson's disease: A potential role of dairy products in men

Auteurs : Honglei Chen ; Shumin M. Zhang [États-Unis] ; Miguel A. Hernán ; Walter C. Willett [États-Unis] ; Alberto Ascherio

Source :

RBID : ISTEX:2482FB64E4ECB74AE498D1C33AFAE43D421EAFAD

Abstract

Diet may play a causative role in Parkinson's disease (PD), but potential associations between diet and PD risk rarely have been assessed in prospective studies. We investigated associations between food intakes and PD risk in two large prospective cohorts in which 210 incident PD cases in men and 184 in women were documented. A positive association was found between dairy intake and PD risk in men (relative risk [RR] comparing extreme categories, 1.8; p trend = 0.004), but not in women (RR, 1.1; p trend = 0.9). No other food groups were associated with PD risk in either men or women. Further analyses among men showed significant positive associations with PD risk for intakes of several dairy foods as well as dairy calcium (RR, 1.5; p trend = 0.02), dairy vitamin D (RR, 1.6; p trend = 0.004), dairy protein (RR, 1.6; p trend = 0.01), and lactose (RR, 1.8; p trend = 0.002), but not dairy fat (RR, 1.1; p trend = 0.4). Intakes of calcium, vitamin D, and protein from other dietary or supplemental sources were not related to PD risk in men. Our results suggest that higher intake of dairy products may increase the risk of PD in men; however, this finding needs further evaluation, and the underlying active components need to be identified.

Url:
DOI: 10.1002/ana.10381


Affiliations:


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